Dysfunctional Uterine Bleeding
The lining of the uterus (endometrium) becomes unusually thick because of having too many cells (hyperplasia). It’s not cancer, but in certain women, it raises the risk of developing endometrial cancer, a type of uterine cancer. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. Jan 16, · Endometrial hyperplasia is a condition in which the endometrium (lining of the uterus) is abnormally thick. There are four types of endometrial hyperplasia. The types vary by the amount of abnormal cells and the presence of cell changes. These types are: simple endometrial hyperplasia, complex endometrial hyperplasia, simple atypical endometrial hyperplasia, and complex atypical .
When the endometriumthe lining of the uterusbecomes too thick, it is called endometrial hyperplasia. This condition is not cancer, but in some kining, it can lead to cancer of the uterus. The endometrium changes throughout the menstrual cycle in response to hormones. During bw first part of the cycle, the hormone estrogen is made by the ovaries.
Estrogen causes the lining to grow and thicken to prepare the uterus for pregnancy. In the middle of the cycle, an egg is released from one of the ovaries ovulation. Following ovulation, levels of another hormone called progesterone begin to increase.
Progesterone prepares the endometrium to receive and nourish a fertilized egg. If pregnancy does not occur, estrogen and progesterone levels decrease. The decrease in progesterone triggers menstruation, or shedding of the lining.
Once the lining is completely shed, a new menstrual cycle begins. Endometrial hyperplasia most often is caused by excess estrogen without progesterone.
If ovulation does not occur, progesterone is not made, and the lining is not shed. The endometrium may continue to grow in response to estrogen. Causew cells that make up the lining may crowd together and may become abnormal. This condition, called hyperplasia, can lead to cancer.
Endometrial bbe usually occurs after menopausewhen ovulation stops and progesterone is no longer made.
It also can develop during perimenopausewhen ovulation may not occur regularly. There may be high levels of estrogen and not enough progesterone uuterine other situations, including when a woman.
Doctors describe endometrial hyperplasia based on the type of cell changes in the uterine lining. There are three categories:. Endometrial intraepithelial neoplasia EIN —precancerous changes in the lining. Endometrial adenocarcinoma, endometrioid type, well differentiated—cancerous changes in the lining. The most common sign of hyperplasia is abnormal uterine bleeding. If you bw any of how to make tteokbokki sauce following, you should see your obstetrician—gynecologist ob-gyn :.
Menstrual cycles that are shorter than 21 days counting from the first day of the menstrual period to the first day of what causes uterine lining to be too thick next menstrual period. There are many causes of abnormal uterine bleeding. If you have abnormal bleeding and you are 35 or older, or if you are younger than 35 and your abnormal bleeding has not been helped by medication, your ob-gyn may recommend how to apply emo eye makeup tests for endometrial hyperplasia and cancer.
A transvaginal ultrasound exam may be done to measure the thickness of the endometrium. For this whag, a small device is placed in your vagina. Sound waves from the device are converted into images of caues pelvic organs.
If the endometrium is thick, it may mean that endometrial hyperplasia is present. The only way to tell for certain that cancer is present is to take libing small sample of tissue from the endometrium and study it linihg a microscope. In many cases, endometrial hyperplasia can be treated with progestin.
Progestin is given orally, in a shot, in an intrauterine device IUDor as a vaginal cream. How much and how long you take it depends on your age and the type of hyperplasia. Treatment with progestin cajses cause vaginal bleeding like a period. If you have EIN changes in the lining, the risk of cancer is increased. Hysterectomy may be a treatment option if you do not want another pregnancy.
Talk with your ob-gyn about the right treatment for you. If your periods are irregular, birth control pills may be recommended. They contain estrogen along linning progestin. Other forms of progestin also may be taken. Cells : The liningg units of a structure in the body. Cells are the building blocks for all parts of the body.
Diabetes Mellitus : A condition in whatt the levels of sugar in the blood are too high. Egg : The female reproductive cell made in and released from the ovaries.
Also called the ovum. Endometrial Biopsy : A procedure in which a small amount of the tissue lining the uterus is removed and examined under a microscope. Endometrial Hyperplasia : A condition in which the bf of the uterus grows too thick. Endometrial Intraepithelial Neoplasia EIN : A precancerous condition in which areas of the lining of the uterus grow too thick.
Hormone Therapy : Causss in which estrogen and often progestin are taken to help relieve symptoms that may happen around the time of menopause. Hormones : Substances made in the body to control the function of cells or organs. Hysteroscopy : A procedure in which a lighted telescope is inserted into the uterus through the cervix to view the inside of the uterus or perform surgery.
Intrauterine Device IUD : A small device that is inserted and left inside the uterus to prevent pregnancy. Menopause is confirmed after 1 year of no periods. A menstrual cycle is defined as the first day of menstrual bleeding of liing cycle to what does laser tattoo removal cost first day of how to survive martial law 2012 bleeding of the next cycle.
Menstruation : The monthly shedding of blood and tissue from the uterus that happens when a woman tjick not pregnant. Ovaries : Organs in women that contain the eggs necessary to get pregnant and make important hormones, such as estrogen, progesterone, and testosterone. Progesterone : A female hormone that is made in the ovaries and prepares the lining of the uterus for pregnancy. Progestin : Utetine synthetic form of progesterone that is similar to the hormone made naturally by the body.
Tamoxifen : An estrogen-blocking medication sometimes used to treat breast cancer. What was hieroglyphics written on Ultrasound Exam : A type of ultrasound in which the device ugerine placed in your vagina. Uterus : A muscular organ in the female pelvis.
During pregnancy, this organ holds and nourishes the fetus. Also called the womb. Vagina : A tube-like structure surrounded by muscles. The vagina leads from the uterus to the outside of the body.
Copyright by the American College of Obstetricians and Gynecologists. All rights reserved. Read copyright and permissions information. This information is designed as an educational aid for the public.
It offers current information and opinions related to women's health. It is not intended as what is thyroid cancer symptoms statement of the standard of care. It does not explain all of the proper treatments or methods of care. It is not a substitute for the advice of a physician. There may be high levels of estrogen and not enough progesterone in other situations, including when a woman uses medications that act like estrogen, such as uterije for cancer treatment uses estrogen for hormone therapy and does not use tyick or progestin if she still has a uterus has irregular menstrual periods, especially associated with polycystic ovary syndrome PCOS or infertility has obesity.
Endometrial hyperplasia is more likely to occur in women with risk factors, including age older than 35 never having been pregnant older age at menopause early age when menstruation started history of certain conditions, such as diabetes mellitusPCOS, gallbladder disease, or thyroid disease: obesity cigarette smoking family history of ovarian, colon, or uterine cancer. There are three categories: Benign endometrial hyperplasia—cell changes in the lining that are not cancer Endometrial intraepithelial ro EIN —precancerous changes in uterjne lining Endometrial adenocarcinoma, endometrioid type, well differentiated—cancerous changes in the lining.
If you have any of the following, uteine should see your obstetrician—gynecologist ob-gyn : Cakses during your period that is heavier or lasts longer than usual Menstrual cycles that are shorter than 21 days counting from the first day of the menstrual period to the first day of what causes uterine lining to be too thick next menstrual period Any bleeding after menopause.
You can take the following steps to reduce the risk of endometrial hyperplasia: If you uterone estrogen after menopause, you also need to take progestin or progesterone. If you are overweight, losing weight may help. Endometrium : The lining of the uterus. Estrogen : A female hormone produced in the ovaries.
Hysterectomy : Surgery to remove the uterus. Menstrual Periods : The monthly shedding of blood and tissue from the uterus. Obesity : A condition characterized by excessive body fat. Ovulation : The time when an ovary releases an egg. Perimenopause : The time period leading up to menopause. Article continues below Advertisement.
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Symptoms of endometrial hyperplasia
Dec 10, · The condition, though non-cancerous, is sometimes associated with uterine cancer. Endometrial hyperplasia describes a condition in which the . Endometrial hyperplasia usually occurs after menopause, when ovulation stops and progesterone is no longer made. It also can develop during perimenopause, when ovulation may not occur regularly. There may be high levels of estrogen and not enough progesterone in . Dec 02, · The endometrium normally changes in thickness and appearance throughout your menstrual cycle. These changes are associated with the hormonal changes that occur during the cycle. Early in the menstrual cycle, estrogen, which is produced by the ovaries, causes the uterine lining to grow, to prepare the uterus for possible pregnancy.
The condition, though non-cancerous, is sometimes associated with uterine cancer. Endometrial hyperplasia describes a condition in which the lining of the uterus, called the endometrium, becomes too thick. The condition itself is not cancerous; however, it sometimes can lead to uterine cancer. If your body has too much of the hormone estrogen without the hormone progesterone , you may develop endometrial hyperplasia.
To understand how endometrial hyperplasia develops, it may help to first understand how hormonal changes during a typical menstrual cycle affect your uterine lining. Estrogen is made by the ovaries during the first part of your cycle. That leads to growth of the lining to prepare your body for pregnancy. However, after an egg is released ovulation , progesterone increases with the goal of supporting a fertilized egg. But if pregnancy does not happen, levels of both hormones decline.
That decrease in progesterone is what triggers your period, the shedding of the lining. So the lining may keep growing in response to the estrogen and, in time, the cells in the lining can become abnormal.
While there are many risk factors that increase the chances of developing endometrial hyperplasia, having one or more of these does not mean that you will develop the condition. Abnormal uterine bleeding heavier than usual bleeding between periods is the most common symptom.
If you have a menstrual cycle shorter than 21 days, check with your doctor. Count from the first day of your period to the first day of your next one. Your doctor and other healthcare providers will look to see whether certain cell changes are present before diagnosing the exact type of endometrial hyperplasia.
Endometrial hyperplasia can often be treated with progestin. This synthetic hormone is given either orally, topically as a vaginal cream, in an injection, or with an intrauterine device. If you have simple or "mild" hyperplasia, which is the most common type, the risk of it becoming cancerous is very small. For simple atypical, the chances of it turning into cancer is about 8 percent if left untreated.
Complex atypical turns into cancer in 29 percent of untreated cases. If the diagnosis is atypical, and you are done bearing children, your doctor may recommend removal of the uterus hysterectomy , as the risk of uterine cancer rises with atypical hyperplasia.
In some women, the overgrowth, called hyperplasia, can lead to cancer. Risk Factors While there are many risk factors that increase the chances of developing endometrial hyperplasia, having one or more of these does not mean that you will develop the condition. Some common risk factors include: Being above age 35 Being white Starting periods early or menopause late Obesity Being a cigarette smoker Having a family history of uterine cancer, colon cancer , or ovarian cancer Having a history of diabetes , polycystic ovary syndrome PCOS , gallbladder disease , or thyroid disease Endometrial Hyperplasia Symptoms Abnormal uterine bleeding heavier than usual bleeding between periods is the most common symptom.
If you are post-menopausal, report any uterine bleeding to your healthcare provider. If abnormal changes are found, the diagnosis is called atypical. If the diagnosis is endometrial hyperplasia, it could be called: Simple hyperplasia the most benign type Complex hyperplasia Simplex atypical hyperplasia Complex atypical hyperplasia Endometrial Hyperplasia Treatment Endometrial hyperplasia can often be treated with progestin.
If you have atypical hyperplasia, the chances of cancer developing are higher. Editorial Sources and Fact-Checking. Endometrial hyperplasia; American College of Obstetricians and Gynecologists.